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Seung U Kim Selected Research

Carboxylesterase (Hydrolase S)

11/2016Tumor-specific gene therapy for pancreatic cancer using human neural stem cells encoding carboxylesterase.
1/2016Human Neural Stem Cells Overexpressing a Carboxylesterase Inhibit Bladder Tumor Growth.
2/2012Human neural stem cell tropism to metastatic breast cancer.
9/2010Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme.
1/2007Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma.

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Seung U Kim Research Topics

Disease

59Neoplasms (Cancer)
01/2020 - 06/2005
22Glioma (Gliomas)
01/2015 - 01/2004
21Stroke (Strokes)
02/2016 - 09/2004
17Brain Neoplasms (Brain Tumor)
01/2015 - 06/2005
16Brain Ischemia (Cerebral Ischemia)
02/2016 - 09/2003
15Spinal Cord Injuries (Spinal Cord Injury)
01/2015 - 01/2007
14Alzheimer Disease (Alzheimer's Disease)
10/2020 - 09/2003
14Parkinson Disease (Parkinson's Disease)
11/2017 - 07/2003
14Ischemia
12/2016 - 06/2003
12Neuroblastoma
01/2009 - 08/2002
11Neoplasm Metastasis (Metastasis)
01/2020 - 05/2008
11Nervous System Diseases (Neurological Disorders)
12/2012 - 08/2005
10Inflammation (Inflammations)
11/2017 - 05/2007
10Neurodegenerative Diseases (Neurodegenerative Disease)
11/2017 - 01/2005
9Huntington Disease (Huntington's Disease)
08/2009 - 10/2003
6Cognitive Dysfunction
12/2016 - 08/2007
6Breast Neoplasms (Breast Cancer)
02/2016 - 12/2009
5Glioblastoma (Glioblastoma Multiforme)
10/2020 - 07/2005
5Fibrosis (Cirrhosis)
01/2020 - 01/2012
5Brain Injuries (Brain Injury)
01/2015 - 09/2002
5Hypoxia (Hypoxemia)
01/2013 - 04/2004
5Cerebral Hemorrhage
11/2010 - 09/2003
4Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
01/2021 - 01/2012
4Ischemic Stroke
12/2016 - 05/2007
4Multiple Sclerosis
01/2016 - 08/2005
4Neuroinflammatory Diseases
01/2015 - 07/2010
4Lung Neoplasms (Lung Cancer)
12/2014 - 05/2011
4Disease Progression
05/2014 - 01/2007
4Infarction (Infarctions)
11/2013 - 11/2005
4Gliosis
01/2013 - 10/2004
3Melanoma (Melanoma, Malignant)
04/2019 - 09/2010
3Necrosis
12/2014 - 01/2008
3Carcinogenesis
01/2014 - 07/2005
3Prostatic Neoplasms (Prostate Cancer)
07/2013 - 06/2008
3Memory Disorders (Memory Loss)
04/2012 - 01/2012
2Erectile Dysfunction
04/2021 - 07/2008
2Chronic Hepatitis B
01/2020 - 02/2013
2Pathologic Processes
11/2017 - 01/2011
2Colorectal Neoplasms (Colorectal Cancer)
01/2017 - 06/2013
2Adenocarcinoma
01/2017 - 04/2010
2Pancreatic Neoplasms (Pancreatic Cancer)
11/2016 - 09/2013
2Endometrial Neoplasms (Endometrial Cancer)
07/2015 - 09/2011

Drug/Important Bio-Agent (IBA)

28ProdrugsIBA
01/2020 - 12/2006
24Cytosine DeaminaseIBA
01/2020 - 03/2009
21EnzymesIBA
01/2020 - 12/2006
17Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2018 - 04/2004
14Fluorouracil (Carac)FDA LinkGeneric
01/2020 - 03/2009
13Flucytosine (Ancobon)FDA Link
01/2020 - 03/2009
11InterferonsIBA
01/2020 - 09/2011
10Therapeutic UsesIBA
01/2020 - 09/2007
10Pharmaceutical PreparationsIBA
01/2020 - 01/2007
10Proteins (Proteins, Gene)FDA Link
01/2020 - 06/2005
10LigandsIBA
11/2017 - 01/2004
10CytokinesIBA
01/2017 - 10/2002
9Chemotactic FactorsIBA
01/2020 - 09/2010
9Irinotecan (Camptosar)FDA LinkGeneric
11/2016 - 12/2006
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2011 - 01/2004
7SurvivinIBA
01/2011 - 01/2004
6Interferon-betaIBA
02/2016 - 01/2007
6Neuroprotective AgentsIBA
01/2014 - 10/2003
6CaspasesIBA
03/2010 - 01/2004
5CM-DiIIBA
04/2019 - 01/2007
5Carboxylesterase (Hydrolase S)IBA
11/2016 - 01/2007
5Transcription Factors (Transcription Factor)IBA
01/2016 - 05/2007
5Conditioned Culture MediaIBA
02/2012 - 04/2008
5Caspase 3 (Caspase-3)IBA
01/2011 - 01/2004
4Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2021 - 06/2008
4AlbuminsIBA
01/2020 - 07/2008
4DNA (Deoxyribonucleic Acid)IBA
01/2020 - 01/2014
4CollagenIBA
03/2015 - 01/2012
4EsterasesIBA
12/2014 - 12/2011
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2014 - 06/2005
4Nerve Growth Factors (Neurotrophins)IBA
05/2013 - 07/2008
4Interleukin-6 (Interleukin 6)IBA
02/2012 - 01/2008
4Death Domain ReceptorsIBA
01/2011 - 09/2007
4Interleukin-8 (Interleukin 8)IBA
09/2010 - 02/2005
3Amyloid beta-PeptidesIBA
11/2017 - 09/2003
3Brain-Derived Neurotrophic Factor (BDNF)IBA
12/2016 - 11/2010
3Peptides (Polypeptides)IBA
01/2015 - 10/2004
3Messenger RNA (mRNA)IBA
01/2015 - 07/2005
3AntibodiesIBA
05/2014 - 12/2008
3Cholinergic Agents (Cholinergics)IBA
05/2013 - 01/2012
3Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
10/2012 - 09/2004
3Glial Fibrillary Acidic ProteinIBA
02/2012 - 07/2005
3Complementary DNA (cDNA)IBA
01/2007 - 09/2004
3Quinolinic AcidIBA
07/2005 - 10/2003
2Antiviral Agents (Antivirals)IBA
01/2020 - 02/2013
2Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
01/2017 - 06/2008
2Biological ProductsIBA
01/2016 - 07/2013
2RNA (Ribonucleic Acid)IBA
03/2015 - 01/2013

Therapy/Procedure

57Therapeutics
01/2020 - 01/2005
52Transplantation
04/2021 - 06/2003
11Cell- and Tissue-Based Therapy (Cell Therapy)
01/2016 - 01/2007
8Drug Therapy (Chemotherapy)
01/2016 - 07/2007
5Radiotherapy
05/2013 - 07/2007
4Intravenous Injections
01/2018 - 01/2012
4Cell Transplantation
01/2016 - 09/2003
2Intranasal Administration
10/2020 - 12/2012
2Intraperitoneal Injections
09/2016 - 07/2015
2Immunotherapy
01/2016 - 12/2009